I kind of wonder if an 485 HP motor could be run on a carb and still be grandmother approved to drive and return 22+ mpg. I am sure a 750 DP would work fine, but I bet it would be hard to get it to run clean all the time, slightly finicky when cold and return (at best) 18 mpg. Now take that same motor and carb and sell it in all 50 states and see how well it works when the climates are so radically different.
I don't think we would have Scat Packs and Hellcats if the OEM's had stayed with carbs. I agree they moved that way due to emissions, but I think it opened whole new chapter in performance in the end.