Strange Noise, Driveshaft?

Yes ^^^
Then grab the pinion yoke by hand, with the rear wheels off the ground and roll it over by hand to see if you can feel anthing odd in the reat end bearings or gear sets.

From the sounds of your description possibly cold be the ring gear moving on the differential housing. Bolts just starting to loosen up from hard use and working that ring gear back and forth under acceleration and deceleration.

Just got the center section from Dr Diff, online. Brand new race 8.75. I can jack the back up and look for play or noise this coming week. Hoping its a U-Joint.