Richard Holdener to test the Piston Reversal theory

OEM is offset
Aftermarket is centered

Exactly. So reversing aftermarket (performance) pistons won't make a bit of difference.

As for reversing factory pistons, which are offset to reduce piston slap when cold, that is a trick that's been in the Mopar Performance Engine Manual since I was a young man. Uncle Tony didn't come up with the idea on his own. Reversing the factory piston reduces friction some (probably small) amount. How much performance is gained, don't know, but any kind of performance build is gonna replace the factory pistons anyway, so why worry about it unless you're on a super tight shoestring budget?