Degreeing a Cam, or not.....

Do they open and close at the same time as #1?

That's a good question. Probably going to have a different open and close, start/stop degree cause the crankshaft with be in a different position on those other cylinders.

Can do the check on cylinder #6 if not too much trouble to get that next valve cover off.

#6 is exactly 180° opposite of #1 as to when it fires. (at least it is on the small blocks) big blocks turn the distributor the opposite way, so you are going to have to check this. Same firing order as the small blocks, I don't know right now. Others will probably chine in. (Looks like @oldkimmer confirmed this above ^^^)

After testing .050 on #1, roll the crankshaft over 360° to compression TDC on #6.
Then do your .050 test again on that cylinder.

Then your centerline numbers should be the same between the 2 cylinders.

This gets to be a bit of a brain tease, the numbers of the centerlines should be the same.

You are smart enough to figure it out, when the numbers all start matching up it will make sense to you.

So far, so good.