Advice on Pinion Yoke Change

I am changing my pinion yoke and seal because of a leak I noticed after I got back from Carlisle. I ordered a 10 spline yoke, a seal, and a u-joint from Dr Diff. I have a 741 case. I am wondering if I will be able to loosen the nut. Can I get the yoke out without a puller? Should I drain the diff before I change the yoke and seal? Any tips will be greatly appreciated. Thanks FABO.