Best 4bbl

Never tuned a carb in my life... That I can remember, anyway. Been out of the game for 30 plus years
Are you just talking turning the mixture screws till it's right..?
I do remember having a 750 on my stock 72 318 Demon back in like 1985... If I remember right, it ran GREAT and launched when the secondaries kicked in..but after a while it didn't run right..
well, besides the idle mixture screws..... there is... just to name a few....
Many times a carb can run "good" out of the box. No carb was set up from the factory for your specific car except the carb it came with from the factory.