Problem with Holley 4 bbl

Does the engine die when you seat the idle mixture screws?
Nope, stays running. No reaction at all to mixture screw changes.
Does it have adjustable air bleeds and fuel restrictors?
No adjustable air bleeds. Just a stock Holley 3310.
The power valve could be OUT and it would not affect idle since no signal is at the boosters to pull fuel in. So you can rule the PV out even if it's buster all to hell.
My understanding of the Holley PV is that at idle the PV has no affect on enrichment since it only adds fuel via the boosters. However, a blown PV can leak fuel past the diaphragm though the vacuum port and into the manifold.

The wrong PV can cause problems when transitioning from idle to the mains. At least that's what I've been told.