Turbo....

How much difference is there if all else is the same except running the carb as a draw thru vs as a blow thru?
I know about brass vs plastic floats, but I'm talking besides that. If (and that's a BIG if) I were to go turbo on my build I was looking at draw thru.
The biggest problem with draw thru, is you cannot run a charge cooler. You don't want a big radiator filled with fuel/air mix, waiting to explode if you have a intake backfire. You would have to rely on water/meth injection.