Turbo....

There's no way I'd do it without an intercooler.....but you know what my biggest hangup is? So far I've not seen but maybe ONE turbo slant 6 that didn't look like *** with all the hoses, lines and whatnot running everywhere. That's the ONE thing that'll keep me N/A unless I can find tome REAL NEAT installations to mimic. .....and I mean REAL DAMN NEAT.

Have you considered a remote set-up? those can be pretty neat and tidy.
With your engine already having a higher compression-ratio,you sorta have the bottom-end covered and you can use the longer pressurized return-pipe as a form of charge cooler, or hide it in a Lake-pipe.
Or how about a 2-stage system?
One thing that might be in your slanty's favor, is the actual Force on the top of that 3.4xx" piston when the ignition fires. Whatever psi is there, the actual force would only be 85% of what it would be on a 4incher. I wonder how you could exploit that, with the super-long stroke?