Sudden Power Loss (opinions)

. I have a laser thermometer but i don't have headers just stock manifolds so i don't think i'll get an accurate read of the exhaust temps would I since they all dump into the manifold
I have checked my stock 273 and I get 8 distinct temperature signatures. Oddly the 2 front most cylinders (1 and 2) typically read 50 deg hotter than the rest like 425 vs 375. ( I'm going on memory so don't quote me on the actual numbers)

As for compression I did a test a few years ago (cold and dry) and barely got 110 on most cyl and 125 on 1 cyl. 150,000 on the last rebuild.