Would a single-point distributor give up anything with respect to performance to a dual-point distributor for a strictly street/highway application? Thank you.
IMO yes, but maybe not for the reason you think.
If you have a good one WITH a vacuum advance, you can install a high current coil and open up the plug gaps to .055 (or more). This will allow you to lean the cruise circuit out, and then give the engine the timing it so desperately wants; bottom line is more cruise torque and more importantly more steady-state MPGs. And probably less oil consumption and longer lasting rings.
The Big Yellow square-top Accell SuperCoil comes to mind. It helped one of my combos achieve over 30 mpgs; allbeit with electronic ignition, and double-overdrive..