Big Inch Small Block

To me, unless there is no budget limit, the 422" 340 or 360 stock-block-based engine is the best CID bang for the buck. That's a 4" crank with 4.100" bore. It needs W2/W5 or Trick Flows with 2.05-2.08" intake valves and roller valvetrain to really be worth it, IMO. The extra cubic inches are nice, but the 4" combos have torque aplenty and still rev quite nicely. You need some serious heads to utilize 476", and lots MORE MONEY than even an R-block!
4.100" bore is not something that many 340/360 blocks will be able to safely handle is the issue with that.......at that point you may as well just pull your pants up and pony up for an R block and be done with it.