Has anyone ever run 17x8.5 +10 on the front? What tire worked for you?

For higher offset wheels, the biggest obstacles are going to be the outer tie rod ends like 72bluNblu said, and the upper control arms when the suspension droops. Low/negative offset is when you start hitting the lower corners of the fenders when turning, and the top arch when turning under compression.
Here is the site I used when determining my setup.
Wheel Offset Calculator