Advice on sealer for insert after stripped water pump/timing cover bolt hole

Never knew it was water soluable. I know it works on parts submerged in water though. It has to cure before submerging it.
I didn't know if there was any standing water in the block. If there is water in the block the water will wash out the Locktite before it dries. Once it dries (in the absence of water) it should be OK.