Cam / Compression Ratio

I'm looking at Howard's 255* / 261*. If I was to have a 9.42:1 compression ratio the dynamic is 6.43:1, is this a safe dynamic compression ratio for the cam I mentioned? No parts bought yet.
Thats pretty low. Ideally your want 7:1- 8:1. Thats a pretty aggressive cam for a street car. What is the rest of the combo? Auto manual rear gear engine etc?