Can I use B or C body manifolds fore better flow on my sleeper GTS?

Imo, wondering how much power “can be made” while retaining the manifolds is the wrong approach.
On a big cube high CR race combo(for FAST), they’ll support over 600hp.
But that isn’t relative to what most street guys are doing.

The question should be, can I make the power I want with my proposed build while retaining the ex manifolds?

If the expectations and the build plans are on the same page, you should be good.
On the other hand, If you’re trying to make 500hp+ on pump gas with a hyd cam and ex manifolds....... you’re probably going to be disappointed.

I smell what your stepping in
The manifold is attractive because of the obvious reasons, budget being one.

If we were to have a stock stroke (gasp) 440 at +.04 with 10.5 comp and a .245 @ .05 / 108 sep cam and a good head (stealth) or better.
what is the "loss" of the manifold..?