“Best” all around axle ratio: ~450hp w/ A904?

I will only say this about that: IN MY EXPERIENCE, every time I took gear out of my car (I have had 4.56s, 4.11s, and the current 3.91s) there was no significant difference in 60ft or quarter, and every time I moved the shift point down, it went faster. Probably as a result of a severely head limited 440. I've never run a small block mopar, so someone else's experience can be quite different.....

Well, you changed 2 things there.

YOu can't change gears without a change in one or more of the things I mentioned earlier. Trap RPM or trap gear have to change. x gear at x speed change with gear ratio. That isn't even debatable.

One thing that struck me here was lowering of the shift point. With a big block, most people spin their engines much farther than where they make power. Even my engine with a pretty large roller cam, full ported oversized valve heads, ported single plane, etc peaks at 5,900.