detonation / knock issue on 340

I don’t get offended, I am asking for help and appreciate the advice. I had a ton of Experience way back in the late 80’s early 90’s with thermoquads ( I used to call them thermo bogs ) but damn when those secondary’s kick in. It’s just been a while. I have zero experience with holleys but have learned a lot over the last few weeks. Just really want something that will be an easy use. Not looking to run 1/4 mile times or get every horse out of the motor.
If you want something easy peasy, I suggest looking at the Quick Fuel carburetors. They have so much MORE adjustability than the old Holleys, it's pitiful. I have a 450 on a slant six and it runs fantastic.