Cam shootout mild engine, on 350 still useful.

Nope
Never see results the other way

My 340 was 11.4-1, ported Edelbrocks and a Weiand X-Cellerator with a 236/242 @ .050°, .590ish lift hydraulic and it wasn't soft on the bottom even with 3.55's. I'd say that cam in a low compression 318 and it would be pretty doggy down low.