To Turbo or Supercharge

Depends on exactly what your talking about, durability and or 400hp?
Not saying it's easy but 400 hp doesn't sound like a pie in the sky number especially if going the turbo route. As for can the bottom end take it, I would believe so unless you point out some weakness?
I don’t think the bottom end is a problem at 400hp. I do think it will take more than 14 psi or so to get to the 400hp mark and it’s been proven time and time again that the slant head bolt arrangement and size is just not up to the task. Like I said twice now, it IS doable and I hope the op does it. But you ain’t gonna screw a slant together with shelf parts and cram 15 pounds in it and have a reliable 400hp.