The best method I've found is to hold your phone over the carb and video it while someone mashes the throttle. You will see/hear what happens. Is the pump shot late? Too short? Too long?? (Another member on here was doing this video method and I picked up on it and found it quite helpful.)
I've found that the pump shot is usually too short and the bigger 50cc pump with a smaller rear nozzle (33-35) makes for a longer shot that carries through the transition. My 408 has an 850 Holley-style with a Super Victor so that's how I solved the riddle. Has 2 50cc pumps and 37 shooters in front and 35 in back (both are tibes shooters).
Of course pump cams and hole position of those cams also matters. I find that hole position 2 is useful if you stage the car with the throttle partly open (like I do holding it at about 2200-2400 rpm). Position 2 usually gives you more of a given cam whereas position 1 is already partly "used up" at that throttle position.
As for jets, I'm at 81 frt & 82 rear. Picked up 1/2 mph when I leaned the front out so gonna lean it out again and see what happens. Plugs still look dark so we shall see....