The trouble with breakers is they can take a long time to trip, and by then there might be a fire. EXAMPLE Our power wheelchairs (24V) use a pair of 70A breakers to feed the system. When I test new drive modules, I stop the chair against the building and firewall the joystick. I do this both front and rear for about 10-15 seconds. These are huge high capacity LiFePo batteries. THEY WILL DRAW over 200A during this time AND WILL NOT NORMALLY pop either breaker!!!!
The trouble with fuses is that sometimes they pop TOO fast. The bigger things get, the more difficult things get. The LAST thing you want is "that critical time" (driving at night, trying to start the car in a tense situation, whatever) and have a critical fuse/ breaker open.