Port-o-sonic or Holley Street Dominator?

You'll be close to that by the time you get bungs machined and welded into an existing manifold and have to get custom fuel rails made up- and still be saddled with a "compromise" manifold. Then there's the throttle body adapter and other miscellaneous hardware that's included in the Hughes kit (which also accepts stock fuel rails). Not to mention that the LA manifolds that you mention won't work with the Magnum serpentine drive, requiring you to swap to the LA TC cover, water pump and v-belt drive. It adds up fast.
Do the Speedmaster heads you're looking at take LA or Magnum intakes?
Sounds like you've been there!