Holley Power Valve Experimentation

What is the application that would need a greater than 10.5 PV ?
Definitely a vehicle that sees street action. If you drove two identical vehicles: one with a “Holley method” of 1/2 of idle vacuum and the other one done by 1/2 of cruise vacuum you would see immediately which is the correct method. Most obvious realization would be at various part throttle (primaries only) operation. But you can’t just slap in a higher number PV and roll. You have to tune all the circuits, one at a time in correct sequence. Seeing/feeling is believing.