Fuel line routing through front fender well

The other consideration is snaking the line through the space between the bottom of the firewall and the frame rail.
This is what I did.
PTFE braided line from the filter/regulator mounted on the frame rail near the tank, through the crossmember, up to the top of the inner fender.
1 line, no kinks, rubber grommets in the crossmember, rubber hose and velcro heat wrap over the line as it snakes through the firewall/frame rail area.