What could cause this? 360 problems ####update####

I’m not sure which combination of marks will end up with the cam retarded a “bunch”.

The typical screw up is the crank key straight up, lined up with the dot on the upper gear pointing straight down.
This makes the cam 2 1/2 teeth(about 35*) advanced.
I've seen this exact scenario in person three times... Guys who have built lots of GM & Ford engines expect the keyway to be straight up... Their general knowledge is fine but when you assume something it usually bites you on the ***...