Hypothetical build questions…

You say you want to drive it "anytime anywhere", your words. That sounds like you want to drive it a lot. To that end, I would look for something with non modern style lobes. Something with "slow and lazy" ramps compared to modern grinds. In the end, you'll be happier and so will the valve train. Maybe an NOS grind from Erson, or like what I have in Gladys, my Ford truck, a Crane Fireball. Maybe one of the old Crower Hydraulic Hauler grinds or one of their Ultra Beast cams. Maybe an old Isky grind. If you go flat tappet, whether solid or hydraulic, I would sure try to find something old and NOS.