cyclic drivetrain vibration

What is TCC?

What I don't get is that if it were something in the driveshaft, rear end, rear tires, why would it go completely away in overdrive? All that spins the same speed at the same mph no matter what gear you are in...

I haven't used the lock-up converter hardly at all. Both the overdrive and the lock-up are actuated by a pair of switches which grounds one of those wires from the trans when pressed. No computer or automatic engagement of any kind that I am aware of...

Trans is freshly and completely rebuilt.

I don't know about the O/D but whenever a customer came in and said his car did "whir-whir-whir" at hiway speed, went away faster than "x" speed, I knew from my Dart experience it was a binding or brinelled joint.
I would always confirm customer complaint, and u-joint or steady bearing was usually the prob. (Harmonic vibration?)
Good luck