Is it possible for 318 to run with dist. 180 deg. off ???

Thank you for all of your help, I was able to make headway on my problem, seems I made the basic mistake on the wiring on the distribution cap had #1 in the wrong spot, have played with timing, running a lot better sounds better also, I can now get to stay running in gear, still having issue with setting the timing as I said, I am using a Innova timing light with adjustable timing built in, when I have the gun set to normal reading I still do not see the timing mark on the bal. and timing marks on engine, when I use the timing advancement on the gun and get it up to 36 deg. then I can see the marks, this a lot better then before when I would need to advance the gun to 98 deg to see the marks, I have set the timing by max vacuum and test drove car has good power no pinging. Also readjusted the Holley carb, I have a small fuel leak on the carb below the rt side bowl area in the area of the vacuum port I hook up the vacuum gauge to, seems like car is running lean but when I work with the air/fuel adjustment screws the engine has most vacuum idles smoother with the screws about 1/4 turn off bottom out of the screws.