Anytime you change the "size" of anything (i.e.: cam, carb, headers, intake plenum, etc.) it can affect the optimum calibration of the carb. Bigger stuff tends to reduce the vacuum signal to the carb so you may need to provide a longer accellerator pump shot and/or bigger squirters and/or more jetting. If you don't have the proper gearing, converter, etc., for the overall combo, the optimized carb calibration with the new parts may not be better/faster than the optimized calibration with the old parts, or not as much faster than it could be. In your case, the bigger cam & intake may provide bigger results on the top end (higher rpm) than at the bottom end. Just gotta test because with so many variables, no combo is the same.
