Is this enough space on my rear wheels? 18” wheels

I mounted up the 18x10 +6 last night. T his is on a stock spring location 8.25 w/drum brakes and a 3/8” spacer on each side. This equals 52.25 spacer to spacer. An A-body 8.75 is 52.625”. I’ll still need the spacer or cut my B-body housing to a 53 - 53.25” flange to flange.
The back lip touches the spring so I would still need spacers on an A-body 8.75.

Does the rear Dr. Diff 11.7” brake kit move the WMS out?

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So typically with an A-body 8 3/4 with stock spring locations a +12 offset is pretty close to where you need to be. The 8.25” is narrower by about a 1/2” per side. The 52 5/8” measurement you’re using is the housing width, not the WMS-WMS measurement. An A-body 8 3/4 with BBP axles is ~57 13/16 wide WMS to WMS. The SBP version is more like 57 1/8”.

With the stock spring locations and BBP axles in an A-body 8 3/4 with drums you typically get about 6” from WMS to spring. With a 1/2” offset you should be a bit better than 6.5” from WMS to spring. As Dion pointed out the disk kit will add another 1/4” or so, now you’re at 6 3/4”. Figure about 1/2” of tire clearance and a 1/2” of tire overhang, and I think that 5.75” backspace is about perfect.