Probably a real dumb question but ....

Are you saying you can’t run big compression and big boost? Why does the “pressure the turbo puts out have to be very limited”? There are no hard and fast rules. You can run 15:1 compression and 50 pounds of boost if you want, just need the right fuel.
Look at the diesels. They start at high compression, and run upwards of 90 lbs boost. It's the total package