Choosing the right stroke for a 340

So it looks like there are some options on the length of stroke one can get in a particular crank rod piston combination. From what I gather.....the longer the stroke the more displacement BUT also the increased risk of interference on the assembly. What are the trade offs to be made? What is your experience with the amount of stroke you have used and recommend etc. Looking for a 340 application in particular.

Lets talk stroke....
""the longer the stroke the more displacement BUT also the increased risk of interference on the assembly.""

My 340 now has 4.00" stroke and a 4.090" bore. The crank and rods are from K1, and my machine shop had to clearance around the rod bolts (ARP 2000-10) which can be seen in the attached pictures.

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