318 with Edelbrok perfomer intake and 600 cfm 4 barrel, what headers please?

It's really up too you, it's a pretty big expense for good ones, can be a bit of a pain and the gains won't be overly huge probably 10-15 hp or so but will be across the entire rpm range, Probably give a little mpg bump.

So is that worth it too you ?

People can make the argument for either way, if you plan on future mods like cam heads etc.. Then it will be more beneficial down the road.