HEI Conversion Question and Holley 2280 Lingering Issue

As I said.....keep the p/up wires separate from the coil neg wire & HT leads.

If you look at the MSD 6 box [ & others ], the p/up wires exit the box on their own...& at the other end of the box from where the coil wires exit. They did that for a reason.....
Similarly, on modules such as HEI & Bosch, the p/up wires are kept way from coil wires.
Twisting p/up wires will do nothing if high voltage transients are nearby [ 200-400v back EMF from the coil ]. I use microphone cable for p/up wires & earth the shield.