High compression 360 set-up

I found out the 360 I swapped into my ‘66 Dart Wagon has 12.5:1 domed pistons and I need some help getting her properly equipped. I have a 650cfm Edelbrock AVS 2 cause that’s what we had laying around. I should also use a higher octane fuel and colder plugs right? There is so many options on plugs so what kind of plugs would you guys recommend. And then I’m having a debate with my grandpa, would it be better to run a higher octane fuel or an octane booster, is one better then the other or is it which one would be cheaper?
Thank you