Can my slant six 3 on the tree be used with 318

It will be some time before I start building my 440 for the Duster , and I have a decent running 318/727 combo that I took out of our 85 D250 I Hemi swapped, So my brain is always going all directions, and was thinking of putting that combo in the 74 Duster where the slant six with the 3 on the tree is. But now I was wondering if the 318 could go on the original slant six 3 speed...