Need new muffler for 318, looking for quiet, what are my options?

Yes.

If I keep it single, should I at least have a 2.5 pipe instead of 2.25 ?
2.5 would help the engine breath a bit more up high in the RPMS. I think the walker Quiet flow is a good choice. Yon can also add a glass pack if you have a long straight area in the exhaust, usually near the exhaust tip is a good location.