Holley Transition Circuit Tuning

Base the main jets on high speed steady state. 60+mph go as lean as the engine will tolerate.
Or what I prefer 'cause I'm chicken is set the jets for based on best time in quarter or Hp on the dyno.
Then set the primary jets for cruising. If it wants leaner for cruising, then richen the PVCR so WOT will be back where it was for best time.
Check the AFR curve in quarter or on the dyno. Is the AFR flat? If not correct with the HSAB. Trick will be figuring out whether primary or secondary sides are the ones to change.

When thats all done, see if the transition from low speed to high speed circuits needs some trimming with transfer slot restrictions.