Good mild 318 build plan?
That cam will be a nice increase across the RPM band over the stock broomstick. The closed chamber heads will bump compression a little as well, which will help you up in the thin air.
Unless you absolutely have your heart set on the ThermoQuad, I'd reconsider. A 600 CFM vacuum secondary Holley or an Edelbrock 1406 may be easier to set up, and a hecuva lot easier to get parts for.