318 Engine Build help

Your cam is not too far from the tried-and-true 284/.528 mech Mopar cam that has been popular for years (because it works). With about 10:1 comp, you should have a nice runner. Lightweight (Titanium) retainers will help with the high ratio rockers.

The 650 DP will do OK, but you will probably be more consistent (if not quicker) with a basic 3310 vac 750 Holley. Run what you've got, but try that next.