Well, I ALWAYS think it's a good time to do what you love. I worked the corporate grind for 20 years before I got fed up and packed it in. Actually, I got laid off, but it was the best thing that ever happened to me. Gave me a chance to open my little "doggie boutique", and while I don't make the money I used to, I'm WAY happier.
Lots of variables in opening up a business, and there are no guarantees. Still, I DO think that people are tired of being frugal. Just remember, the old adage of "location, location, location" being the three most important things in starting a business is absolutely true. Best of luck!
