Yes, a virtual bolt-in set up from Scat or you can use the Mopar 4" crank. 450hp is a very streetable possibility. Some good adjustable roller rockers (Crane Gold Race or Hughes) and a solid cam designed for your components (Clay Smith Cams) and that thing will just scream!
Mild touch-up of the stock heads is all the head required for this level. Better heads and more (solid roller!)cam and 600+ streetable hp is easy! At this level you will wanna run the forged crank!8)
