340ci vs 360ci engine

Just out of curiosity if you made a 318 into a 300+ hp engine or even 400+ hp would you or could you put a 727 trans on it? Im just wondering because im thinking about possibley keeping the 318 when I buy my car the possibly buying a 69 ( charger duster demon not sure yet ) and maybe putting the fixed 318 in that ( or a 360 or 340 ) and selling its 318 or slant 6 or whatever. Im not sure what I should do for a complete set up. So what do you guys think about a 727 trans on a fixed up 318?