Cast Crank Strength

How much spray can a balanced cast crank handle. I'm trying to decide if I wanna go to a stroker motor or build another 318ci motor that takes a about a 200 - 300hp shot of nitrous. Basically I'd like to see the 10's out of my street/strip Duster. I'm running 11.85's now with a 100shot and I figure a 200hot should get me into the 10.90's along with better compression, head porting and a roller cam. I wanna keep the motor on pump premuim but I don't mind mixing in some race gas for the track for nitrous use. I think if I get some H-beam rods and some good pistons; have the rotating assembly balanced the cast crank should be fine. I know of guys running more power on the cast stroker cranks. Also anyone have any experience with the KB pistons and spraying over 150 shot on them? I know you have to set the ring end gap to their specs. I have always been told a 100-125 shot was about max with them. I'm leaning towards the nitrous motor because I can make it have great street manners and run on pump gas, cost less money cause I already have some of the stuff and I wouldn't need any more block machining and I can up-grade stuff in steps. Would I even need H-beam rods? They would probably be lighter that a set of stockers that were re-worked.