FB timing issues

Yeah I saw the post earlier today as well. I would take a screenshot and post it here but unfortunately he took it down. His claim was that when you switch a stock 2 bbl 318 to a 318 with 360 heads and a 4 bbl intake and carb WITHOUT touching the distributor, the time goes WAY off and the timing marks on the balanced are no longer accurate and a timing light can no longer be used to time the engine, it has to be done by ear. Claimed he’s seen it at least 6 or 7 different times over the years.
was it in a Demon?