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Chamber shape and quench come into play. Conservative timing and colder plugs will be needed.

Using a Strange S-60 housing I bet those are lighter than a converted truck housing, probably by quite a bit.

One would knock first.

http://www.forabodiesonly.com/mopar/forumdisplay.php?f=83

That MPH is solid 12 teens or better. Tire psi and a good burnout or critical.

For the carbie I ran a chokeless Holley 830 annular. More than needed but at my weight it worked good on the street and strip.

Only reason im running what I am is my pistons have no valve reliefs. My buddy did up a 440 with a .585 Ultrdyne at the time and that was such a good running street engine! It went 11.30s in a all steel leaf spring 70 Cuda and 10.50s with a squirt.

That is the cam in my 451 as we speak lol! Never ran 10s but did dip in the 11s a couple times through the muffs and in full street trim at 2300ft.

Ive been running stock 400 rods for 16 years in this motor. 6200 rpm is all she pulls to with the hyd. cam. Upto 600hp I dont see a reason to spend a bunch of money on rods.

Fuel supply needs addressed for sure. What is your distributor and how is your vacuum advance hookup?