Yes you can work on it, one reason I went with epoxy. I had gas pour out of the dart one night when working on it and just wiped it up, no danage to the floor. Used my floor jack and jack stands with no problem, and could find stuff I dropped on the floor very easy after coating the floor. Oil leaking out of the engine, trans rearend, WIPES RIGHT UP.
My thought on U Coat it, they wanted a grand for the 3 kits I needed. Got it done for $1,800, (I got a very good deal) and all I had to do was clean the garage out of all my crap
The floor was shot blast (A MUST FOR LONG TERM ADHESION)
If you are pouring a new floor I would check with an expert on epoxy floor to see what is the best finish surface to apply it to. You do not want it slick, just like painting your car without sanding, it will not stick well
Concrete will need to cure before applying the epoxy.
The worst thing is I had to mop the floor afterwords to keep it looking like it does in the picture. It does get some scratches in it, and if you drag crap across it it will get damaged, but if the coating is thick enough it will not go thru to the floor.
Common sense and it will look good for years to come
I sold the house last year, once I get another house I will again have Mike Epoxy Coat the garage floor