The break point is '72.
'73 and up is basically a pick-up engine with van mounts, so use that as a guide.
That means you have to change the mounts, pan, exhaust manifolds and, possibly pullies and brackets, though some used non-air brackets similar to a car application.
1975 and up also were normally cast crank, but not always.
On the earlier motorhome engines the heads are special, the water pump housing is special, exhaust manifolds, cam, gear-on gear timing components, damper, pistons, even the crank is an 8 bolt extended flange.
No, the crank is NOT like a HEMI crank!
The 413 INDUSTRIAL block (cast # 2658836) was also used in motorhomes and is capable of being bored to a 440's bore size with no issues.
I recently pulled a 440 from a '76 motorhome that was stamped 440 on the ID pad and used the above mentioned INDUSTRIAL block.
Some 1972 413 Motorhome engines used a shot peened 6 bolt, non-extended flange (read: 413/440 car type) crank with standard 'LY' rods, yet still utilized all of the Industrial type accessories out lined above, with the exception of some coming with normal rotation cams that used timing chains and not gear to gear.
Mark.