I disagree Mike. IIRC they are larger on the 308 type castings - might be on others but that casting sticks in my head for some reason.
You can clearance the pushrod holes, yes. I'm pretty sure it's going to be mandatory if you run the hydraulic rollers with the early heads. I know it's needed on the LA RPM heads to run the factory roller lifters. It's best done as part of mock up so you can make sure there's plenty of room, but before the heads are fully "final assembled" because you'll be creating iron dust/filings. Also - if you can afford the best 5/16 diameter you'll save some grinding over using a cheaper 3/8 diameter.